Ayse Ulusoy Selected Research

Synucleinopathies

11/2021	Synapsin Condensates Recruit alpha-Synuclein.
7/2018	In vivo models of alpha-synuclein transmission and propagation.
1/2018	Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease.
1/2018	Long-lasting pathological consequences of overexpression-induced α-synuclein spreading in the rat brain.
1/2018	LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
1/2017	Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections.
3/2016	Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice.
3/2015	Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury.
4/2013	α-Synuclein elevation in human neurodegenerative diseases: experimental, pathogenetic, and therapeutic implications.

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Ayse Ulusoy Research Topics

Disease

17	Parkinson Disease (Parkinson's Disease) 01/2022 - 08/2008
9	Synucleinopathies 11/2021 - 04/2013
5	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2018 - 08/2008
4	Disease Progression 07/2018 - 01/2011
1	Iron Overload 01/2021
1	Cognitive Dysfunction 01/2020
1	Pathologic Processes 07/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2018
1	Inflammation (Inflammations) 07/2012
1	Neuroinflammatory Diseases 07/2012
1	Drug-Induced Dyskinesia (Dyskinesia, Drug Induced) 07/2010
1	Dyskinesias (Dyskinesia) 07/2010

Drug/Important Bio-Agent (IBA)

14	SynucleinsIBA 11/2021 - 01/2010
5	Proteins (Proteins, Gene)FDA Link 11/2021 - 02/2012
3	alpha-SynucleinIBA 01/2022 - 08/2010
3	Dopamine (Intropin)FDA LinkGeneric 09/2012 - 08/2008
2	Neuroprotective AgentsIBA 01/2021 - 08/2011
1	LipidsIBA 11/2021
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2021
1	IronIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2018
1	Oxidants (Oxidizing Agents)IBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA 02/2012
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 08/2011
1	NeurotoxinsIBA 08/2011
1	Therapeutic UsesIBA 08/2011
1	Nerve Growth Factors (Neurotrophins)IBA 01/2011
1	PolymersIBA 08/2010
1	Apomorphine FDA Link 07/2010
1	Levodopa (L Dopa)FDA LinkGeneric 07/2010

Therapy/Procedure

1	Precision Medicine 01/2022
1	Therapeutics 01/2011